ABSTRACT
Background: The use of vaccines is still a crucial defence against the COVID-19 outbreak. Pfizer-BioNTech One of the first vaccinations to reach Iraq was the COVID-19 vaccine, which has grown immensely popular due to its great efficiency. The World Health Organization announced the release of various COVID-19 vaccinations in September 2020. The Pfizer mRNA vaccine was given emergency approval on December 31, 2020. According to the study, the Pfizer vaccination had a 95% success rate. The prevalence of local side effects was higher with the mRNA-based vaccinations (e.g., injection site pain). However, a significant obstacle in the fight against the spread of the coronavirus is the public's vaccination scepticism of the current vaccines. Methods: This cohort study was done between October 2021 and May 2022 to determine the prevalence of COVID-19 vaccine (Pfizer-BioNTech) side effects among individuals who visited primary health care centres in Najaf. Participants were Iraqis from the Governorate of Al-Najaf Al-Ashraf. After the first and second doses of the COVID19 vaccine administered by Pfizer, individuals aged 18 to 50 or older who got the vaccine were monitored at varying intervals. Results: In this study, regarding the side effects of people vaccinated with the Pfizer/ BioNTech vaccine, some side effects were found, the most common of which are injection site pain after the first dose, but after the second dose, the symptoms decreased and seemed to be less than the first dose the temperature became the most common. Conclusions: The most often reported side effects included injection site reactions, myalgia, fever, headache tiredness, and chills. Most symptoms ranged in severity from mild to moderate. © 2022, ResearchTrentz Academy Publishing Education Services. All rights reserved.
ABSTRACT
Background: The World Health Organization (WHO) declared coronavirus disease 2019 (COVID-19) a public health emergency on January 30, 2020. Mass vaccination programs are needed to boost population immunity and prevent COVID-19 pandemic impacts. In this research, we used the Pfizer BioNTech vaccine, which Iraqis prefer above others. Pfizer and BioNTech's BNT162b2 was 95% effective in preventing COVID-19 symptoms and almost 100% effective at preventing severe COVID-19 or hospitalizations, and the US FDA authorized its first EUA on December 11, 2020. Methods: This cohort study was conducted in Al-Manathira Health Center in Al-Najaf Al-Ashraf Governorate from (October 2021 to May 2022). 75 samples (55 males and 20 females) with or without previous infections were collected, and these samples were divided into five groups according to age (18-50 and over). We collected three venous blood samples from the vaccinated. Results: A serological analysis to measure SARS-CoV-2 S1 -RBD IgG and neutralizing antibodies NAbs to SARS-CoV-2 was done by using the CLIA technique SARS-CoV-2 kits, China, which was carried out in the Najaf Specialized Laboratory for Pathological Analysis. In this study, neutralizing antibody (NAbs) and immunoglobulin G (IgG) levels after two doses of Pfizer/BioNTech vaccine increased at a level of 0.05 (p = 0.00001). Conclusions: This study concluded that there were high and gradually increasing concentrations of neutralizing antibodies (NAbs) and IgG after two doses of the Pfizer/BioNTech vaccine. © 2022, ResearchTrentz Academy Publishing Education Services. All rights reserved.
ABSTRACT
Coronavirus disease 2019 (COVID-19), Coronavirus causes severe acute respiratory syndrome (SARS-CoV-2), and has spread around the world as a serious pandemic. The worldwide epidemic of the SARS outbreak was reported in 2002-2003 that the CFR was estimated at 9.6% globally and much lower than the CFR of 6.4% in mainland China, while the MERS outbreak had a much higher rate than the CFR. COVID-19 may present with ARDS and respiratory failure from pneumonia, with or without cardiogenic shock ± distributive. In contrast, airborne transmission may happen through two dissimilar situations and need physical contact between susceptible individuals and infected.